Signs and symptoms of Celiac disease:  In children, the disease is manifested by:



-Digestive disorders, which start since the introduction of flour in food;
- diarrhea, chronic ;
-Steatorrhea (large amounts of fat present in the stool) ;
- Abdominal distention (bloating);
- Abdominal pain ;
- Growth retardation ;
- Weight loss ;
- Intense fatigue ;
- Pallor - which translates anemia ;
- Sudden changes of mood (irritability, depression) ;
- Neurological disorders ;
- Dermatitis (skin disease) characterized by the appearance of vesicles (fluid-containing skin lesions) similar to those of herpes .



2) In adults, onset is sometimes accompanied by intestinal disorders and occurs between 35 and 65 years. When present, symptoms of celiac disease are:
- Chronic diarrhea;
- Flatulence (gas accumulation in the intestine) ;
- Abdominal pain ;
- Steatorrhea (large amounts of fat present in the stool) ;
- Bone disorders such as osteomalacia (bone Removing limescale general, secondary to deficiencies of calcium and phosphorus, or of deficiencies of vitamin D2);
- Bone pain ;
- Weight loss ;
- Asthenia (fatigue intensity) ;
- anorexia (appetite loss);
- Calcium deficiency related bleeding ;
- tetanus (contraction of the extremities) ;
- Dermatitis (skin disease) characterized by the appearance of vesicles (fluid-containing skin lesions) similar to those of herpes ;
- Diabetes Insulin;
- To the spleen;
- Other inflammatory bowel disease (IBD).



Possible Complications of Celiac disease:
If gluten-free regime is not adopted, Celiac disease in its severe forms, can have multiple consequences on health: Lactose intolerance - Thanks to achieve intestinal mucosa, a lactose intolerance can occur. Sometimes it disappears shortly after adopting a gluten-free diet.

Anemia- iron reserves may dwindle as a result of poor assimilation of iron.  Osteoporosis - Poor uptake of calcium and vitamin D leads to loss of bone density leading to osteoporosis.

Kidney stones - to poor absorption of fats train an abnormal re-absorption of oxalate, causing a type of kidney stones (calcium oxalate-based).

Infertility - The risk of infertility in people with Celiac is 12% higher.

Some types of cancer - Celiac disease is associated with an increased risk of intestinal lymphoma, long-term.

Diagnosis: Diagnosis of Celiac disease is difficult to ascertain. Physicians should eliminate the possibility of other more common digestive problems (irritable bowel syndrome, a food intolerance or inflammatory bowel disease). Iron deficiency and folic acid may give clues to diagnosis.  Diagnosis of Celiac disease is established in three stages. The first consists in an immunoassay, to determine the level of antibodies (antigliadina, antiendomissium). High levels of these antibodies shows that the body reacts in excessively to this gluten. This test allows a diagnosis with a sensitivity of 90-95% and a specificity close to 100%.

To confirm the diagnosis, it works on intestinal biopsy which involves taking a piece of intestinal mucosa (most commonly in the duodenum). In case of Celiac disease, the surface is flat fragment taken without villosity.
Adopting a gluten-free diet and following symptoms may also provide information. Digestive disorders and nutritional improvement in terms of adopting a gluten-free regime for the patient, also targeting the diagnostic.

Attention. We recommend consulting a physician before adopting a gluten-free diet. Otherwise, the diagnosis becomes more difficult.