Here is a letter received in writing by a reader with its annotation, research and views on the causes of ALS neuromuscular disease.

"After a search to understand the causes of neurodegenerative diseases have guessed this plausible reality: the cause of neuromuscular disease ALS, is the lack of oxygen to the brain, namely: the reduction of compensation of oxygen to the cerebral cortex motor, which constantly evaluate, quantify, and store their own blood supply, its oxygenation, became later (through its system of self), employee compensation of oxygen that gets doing any intense physical activity, strenuous and continuous over time.

Explain: With the investigation of the Turin prosecutor Raffaele Guariniello we heard that former football players get sick of ALS six times more than the average of other people, this survey was for me an extraordinary confirmation of what I had already guessed because some evidence indicates that now describe.

First show: the symptoms of ALS appear always after a certain time, usually several years after the end of football; the disease never affects athletes while engaged in the same sport.

Second show: goalkeepers do not ever get sick of ALS, the reason for this immunity is clear, the goalkeeper does not include the race, and their cerebral cortex motors are not needed strong compensation of oxygen.

In fact, players who fall ill with amyotrophic lateral sclerosis are the athletes who run more, too tiring, without granting the necessary breaks, breathing incorrectly.

When the athletes running exceed certain limits, their motor cortex neurons require a considerable amount of oxygen these demands for more oxygen is compensated by self-regulation system that has the brain for its blood supply, its oxygenation.

Motor neuron activity is more intense, the greater must be the compensation for oxygen, allowing the neurons in the motor cortex to generate pulses that are transmitted to cells of the spinal muscles operate.

As long as the football player has been in operation, his motor cortex may receive significant compensation of oxygen, but when the athlete completing the sport does not fit with a constant and gradual exercise, the compensation for oxygen is reduced, but Cerebral Motor Cortex Neurons of their being dependent oxygenation obtained compensation for a long time, they can adapt to a lesser amount of oxygen, motor neurons will deteriorate slowly and no longer generate the pulses which activate the muscles, causing progressive muscular atrophy which indicates amyotrophic lateral sclerosis.

Thus we understand that other people sick ALS without being football players, have done any strenuous physical activity, mobility, continuous, because of which have caused the same dependence on oxygen supply to the motor cortex, ending then dramatically intense physical activity for long, their motor neurons will undergo the same reduction of oxygen causes compensatory after some time the ALS. So we know that when you practice an intense and prolonged physical and motor, are indispensable appropriate pauses, breathing properly, then deciding to end it, you should continue gradually with a slight but steady exercise in this way can avoid ALS.

Signs and symptoms of disease ALS

The initial signs and symptoms of disease ALS are: muscle weakness in legs and arms, difficulty in swallowing and breathing as well as speaking, twitching and shortness of breath.