Parkinson's disease is a common neurological disorder, which is estimated to affect over four million people worldwide. Despite all the scientific and medical efforts that were made, it is not yet found a cure to heal patients that suffer of Parkinson's disease symptoms, but the new regimens significantly improve their life’s quality. Contrary to widespread opinions, Parkinson's disease symptoms affect not just the elderly. Although the average age at which diagnosis is 60 years, one of 20 people begin to have Parkinson symptoms even before reaching the age of 40 years. Patients diagnosed at young ages, between 21 and 40 years, suffer from so-called early-onset Parkinson's disease.

-Causes:

Parkinson's disease is caused by destruction or degeneration of neurons that produce dopamine, neurotransmitter substance, responsible for the body's ability to control normal movements. The main area affected is located deep in the brain substance, is called "substantia nigra” (black substance).

-Symptoms Parkinson disease:
Symptoms appear when dopamine levels in the brain decreases by about 20% from normal values. Not all patients have the same symptoms at the same stage of disease. The disease manifests itself very differently from one individual to another; sometimes pass many years to observe a significant limitation of daily activities.

Symptoms become increasingly evident as the disease evolves. An early sign that may indicate (without binding) Parkinson's disease is the invisible hand’s tremor- an inner tremor, without any visible manifestation. Many patients suffering from Parkinson's disease feel well for years until symptoms become bothersome. Parkinson syndrome, the most common being extra pyramidal syndrome, it’s the result of basal ganglia’s damage. In few words, Parkinson's consists of a progressive degeneration of neurons in the brain region that controls muscle movement. Therefore, there are also other several possible causes of Parkinson syndrome which is manifested by symptoms consisting in tremor, rigidity, impaired postural reflexes, the mimic, voice, etc.

Parkinson's disease it’s defined by physical posture "stuck". Patient goes in small steps, like running after his own center of gravity that he do not reach ever. Also, there is impaired natural automatism - no balancing arms in walking, lack of normal leg extension in sudden rocking chair that was placed, with the lack of lift eyebrows with the eyelids to look up. Also, it’s manifested the delayed onset, slow and incomplete reactions mimic, facial posture petrified, passive motility disorders (extra pyramidal contractile), autonomic disturbances (hot flushes, hyper salivation, sweating), speech disturbances (speech is slow, monotonous, with a tendency fighting to silence), psychiatric disorders (depression, anxiety, etc.).

Finally, another sign is essential tremor, consisting of rhythmic oscillations, regular, hands, head, legs, occurring at rest (static) or to attempt to maintain a job, but disappeared during active voluntary movements in sleep.