Niemann-Pick disease is a genetic disease of the metabolism in which the deficiency of the lysosomal enzyme acid –can cause pathological accumulation of lipids in all body cells but mainly in the spleen, liver, lung, bone marrow and brain. The disease is rare, and occurs in all races and both sexes.



Niemann Pick disease is transmitted autosomal recessive, which means that both parents were heterozygous-had one gene mutation present (but clinically healthy carriers of the mutation) and one in four children (25%) - heterozygous-will "inherit" the mutation genes from both parents and will become a patient. The gene that encodes the synthesis is located at chromosome 11p. There have been identified 12 mutations that can cause Niemann-Pick disease type A and type B.

Niemann Pick disease symptoms - The Niemann Pick disease symptoms are varied and differ depending on the type of the disease. There are described four types of Niemann-Pick disease, of which only type A and B are determined by scarcity (types C and D are determined by abnormal transport of cholesterol to brain cells, with accumulation of cholesterol in lysosomes).

Type A Niemann-Pick disease is the most common (almost 80% of cases) and is characterized by a normal aspect of the child at birth, possibly prolonged jaundice. By the age of 6 months there is evidence of hepatic and spleen enlargement and psychomotor retardation; neuropsychological deterioration is rapidly progressive. Manifestations of this disease are:

Eye: "cherry-red spot" in 50% of patients; Respiratory: - recurrent respiratory infections; Lung: diffuse reticular and fine nodular infiltrate; Abdominal: the increase in volume of the abdomen; Liver: hepatomegaly, jaundice neonatal; Spleen: spleen enlargement; Gastrointestinal: vomiting, constipation, difficulty eating; Skeletal disorders: osteoporosis; Neurological: Central nervous system: hypotonia, hyporeflexia, psychomotor retardation; stiffness; Blood: - anemia; "Niemann-Pick cells" in bone marrow biopsy;

Type B Niemann-Pick disease can begin during the infant or child in a routine consultation, the spleen-hepatomegaly, which is progressive and leads to increase in volume of the abdomen, in time, the associated impairment of the lung may be severe; around the age of 15-20 years is normal. Patients with type C Niemann-Pick disease have often prolonged jaundice (up to age 1-2 years) and progressive neuropsychological slow deterioration.

The spleen-hepatomegaly is less important compared with types A and B disease and survival is possible up to adult age. Specific diagnosis of Niemann-Pick disease is determining by the level of activity in leukocytes fibroblast cultures, which is very low (below 5%). In some countries this investigation is not yet available. In the absence of specific examination, histopathological examination of various tissues obtained by liver puncture biopsy= may bring evidence in favor of the diagnosis by revealing Niemann-Pick cell.

Niemann-Pick disease can be present in other diseases such as: Wolman disease, storage disease cholesterol esters or lipoprotein-lipase deficiency. Hematological evaluation can detect a decrease in the number of platelets, white cells and red blood cells. Ophthalmologic examination may reveal, for half of the patients' red cherry spot. Analysis of mutations is possible in specialized laboratories (not yet available in some countries), specifying the mutation is useful for a patient to identify the carriers in their families at risk and prenatal diagnosis.

The Lyme disease is a bacterial infection that is transmitted by a tick bite. Most frequent symptoms of Lyme disease are fever, fatigue, headache and eritema. Because these symptoms are encountered in many other diseases, there must be done a differential examination diagnose.



Isodex scapularis, the deer tick or black tick is the vector infectious bacterium Borrelia burgdorferi. It is responsible for the occurrence of the Lyme disease. It normally lives in mice, squirrels and other small animals.

The tick has three developmental stages: larva, nymph and adult. When an infected tick feeds on blood of a sick animal, and ingest it, the bacteria will live in the intestine. These ticks will then infect other men or animals at their next meal. Most cases of infection occur at the end of spring or summer when the tiny tick nymphs are most active in the environment and human activities are frequent.

The rest live in the fur deer ticks, which do not contract the Lyme disease. The treatment for the Lyme disease consists of antibiotics.

Causes - The deer tick is the principal vector of the Lyme disease but has not been shown whether other ticks may or may not become vectors.

Other modes of transmission of disease: -people contacts; -transmission during pregnancy; -by blood transfusion; -from the animals.

Interpersonal transmission: it has not yet been proven that the disease can be transmitted by kissing, touching or sex with an infected person.

During pregnancy, the disease can lead to infection of the placenta and abortion have not yet been registered, neither negative effects on the fetus. If the mother is treated properly after the transmission of the disease with antibiotics, there should not be any risks.

Although there were not yet registered any cases of infection through blood transfusions, it has been discovered that the bacterium survives in infected blood donations. The patients or infected people can donate blood preserved for 12 months after the last dose of antibiotic treatment.

Pets can have the Lyme disease but there is no evidence that they may become vectors for human beings, instead they bring ticks into the house and garden. The disease is not transmitted through the squirrel or deer meat, but it should still be properly cooked to appropriate temperatures before eating.

Symptoms - The first sign of infection is usually called a circular migratory erythema. It occurs in 70-80% of infected people and the area of the tick bite begins to get red, after a period of three to thirty days. A distinguishing feature of skin is gradual expansion of several days, reaching up to 30 cm. The erythema may become normal colored center as they expand as compared with an ox-eye. It can be warm and painless. Some people develop other flushes in different areas over several days.

Later symptoms of Lyme disease: -fatigue; -chills; fever; -headache; -cramps; -lymphadenopathy. In some cases, redness may be absent. The later symptoms of Lyme disease, left untreated can help the infection to spread to other parts of the body in a few weeks, causing a variety of symptoms:-motor weakness of both sides of the face-Bell's palsy;-severe headache and neck pain due to meningitis;- pain that leads to insomnia;-throb and dizziness due to arrhythmias; -migratory pain to joints. Most symptoms resolve even without treatment.

Some of the pain we are feeling is sometimes the symptom of a disease, but on other occasions it can only be something temporary that is caused by something unimportant and which goes away very soon. If you want to know if your pains are symptoms of severe liver disease, then you should know what that pain is. Generally, symptoms of severe liver disease involve less pain and more coloring, namely yellow.



A "tired" liver is wrapped in fat - After a high fat meal and "sprayed" with alcohol, pain may be caused by bile or pancreas. Many of us sometimes say "My liver hurts, it si from fatigue”. How true is this "saying"? People all over the world have adapted quickly to the fast pace of a market economy, with its continuous efforts. Fatigue and overwork are inherent and occurring in our lives everyday. We need to recognize this and know how to act. The liver, the "laboratory organ”, has at least 9 core functions and summarizes more than 2,500 known substances (and probably 25,000 unknown ones). Therefore, we must understand that the liver, necessarily grows "tired".

The liver has one of the best ways of regenerating the entire body. In particular, fatigue in the body does not create symptoms directly related to "place" where the liver is in the body. I mean, if you have pain in the right part of the abdomen, this does not automatically mean that you are feeling the pain caused by a tired liver. We must not forget, for example, that running in physical education class in school also caused the right side of the abdomen to hurt.

That pain, which disappear once we stopped running, had little connection with the liver, but with the large intestine which forms an elbow near the liver and gas starts going up, pressuring the. The pain is normal there, and not from an accumulation of blood in the liver. We also remember, some of us, that if we eat too much then we feel pain or discomfort in the liver. In principle, this is gall bladder pain. The gall bladder is a neighbor to the liver and its contraction causes noises. Also, the pancreas might be involved in this pain.

The full anatomical structure of the liver organ does not allow the location of sensitive nerve fibers within the liver himself, only on the shell of the liver, which is also called the hepatic Glisson capsule. Thus the liver only hurts in unusual circumstances, when there are abscesses in the liver, when there is a large tumor or when the heart fails to collect blood and lets it accumulate, dialting the liver.

So, to sum it up, symptoms of severe liver disease usally involve other symptoms, aside from the pain. There is jaundice, there is fatigue throughout the entire body, which is to say that the liver causes the fatigue here, not the fatigue causes the liver pain. Also, the stool might be light in coloe. Severe liver diseases include many types of hepatitis, liver cancer, cirrhosis and so on. For these, looking for symptoms on google will not do you much good. If you suspect you are seriously ill, get out fo the chair and go to a doctor. Now.

The Canavan disease primarily affects children of Eastern and Central Europe Hebrew (Ashkenazi) and is an inherited neurological disorder that deteriorates the brain. The Canavan disease is caused by a deficiency of an enzyme called aspartoacilaza (ASPA).



This deficiency leads to an increased level of N-acetilaspartic (NAA) in the brain. NAA causes a chemical imbalance that destroys myelin. Myelin, known as "the white substance” in the brain protects nerves and allows you to send messages to and from the brain. If the chemical imbalance of "white substance" foam is unable to send messages, it causes Canavan disease symptoms.

Signs of Canavan disease usually appear when children are between 3 and 6 months. These include delay in development (motor slowness), the extension of the head, and loss of muscle tone, poor head control, and severe feeding problems. As the disease evolves, the Canavan disease symptoms consist of seizures, blindness, nerve damage and often eye damage, heartburn (gastrointestinal reflux) and dysphasia. Most children with Canavan disease die in the first decade of their life.

Canavan Disease is a genetic disease, an inborn neurological malformation in which the white material of the brain tissue degenerates, leading to spongiform. There is no antidote or a standard course of medical treatment. Canavan disease symptoms (occurring at an early age) include mental retardation and loss of motor skills. Death occurs at ages between 4 and 20 years. Canavan disease is one of the most common degenerative brain disease that appears in early ages. In the Ashkenazi Jewish ethnic group, about 2% of members are carriers of this hereditary disease. Of course, Canavan syndrome occurs also in other ethnic groups.

Ashkenazi Hebrew people in the group, more and more couples require genetic testing before marriage: if none or only one of the prospective parents is carrier of a gene mutation, there was a 25% chance for each pregnancy that the future child to have Canavan disease.

For this reason, DelphiTest GmbH Germany developed a new genetic test based on analysis of oral fluid samples. Customers can easily and without pain take the samples in their home. The samples are then forwarded to the laboratory in Regensburg where the gene coding region will be analyzed. The full analysis costs 400 EUR, - for each member of the couple, as described by Dr. Frank Pfannenschmid.

The Canavan disease is an autosomal recessive disorder: if the child contracted the disease, both parents must be the bearers of defect genes. The Canavan disease is a genetic disease, an inborn neurological malformation in which the white matter of brain tissue to degenerate transforming spongiform. There is no antidote or a standard course for medical treatment. From what we know, there are only two laboratories in the world that offers genetic testing for Canavan disease. These labs require their clients' blood samples to be transported very carefully, requiring high costs.

The genetic test enables the customers to check whether their genes provide increased certainty. Genetic counseling is very important in helping couples who present risks in exploring their family planning options. In America, many rabbis advise young couples to perform the Canavan test. The Canavan disease can be identified by a simple prenatal blood test that determines the absence of ASPA enzyme or mutations in the genes. A second method is measuring the NAA levels in the amniotic fluid, determining the exact NAA levels in amniotic fluid.

Huntington's disease, a neurodegenerative disease, affects 30.000 Americans and is incurable and fatal. But a new discovery about how cells repair DNA indicates a possible way to stop or slow the onset of the disease process. The study was founded by the National Institute for Health (NIH). "What happens often, research touch with a biological process - in this case the enzymes involved in DNA repair - leads to new discoveries about this illness and ways to prevent and deal with them." said Dr. Elias A. Zerhouni, NIH director.



The study was published on April 22, as an advanced online publication in the Nature journal and was led by Dr. Cynthia T. McMurray, professor of pharmacology at the Mayo Clinic in Rochester, Minnesota.Unlike other genetic diseases, symptoms of Huntington's disease usually appear not only to middle aged people, which put scientists on thoughts on the cause of the onset of symptoms and determine whether or not they can be countered, or at least slowed down.

Patients with this disease have a version of a gene called Huntington that carries an extra segment with a certain sequence of repetitive units. If the segment is too large, erroneous gene produces a protein with brain damaging effect. "Huntington's disease is a progressive disease, but no one knows exactly why." McMurray says. "Our work supports the idea of disease progresses when the extra segment increased during non-dividing cells such as neurons."

McMurray's study shows that the inserted segment increased when the cell tries to remove oxidative lesions are caused by byproducts of oxygen breathing. DNA repair enzymes initially manage to repair oxidative damage, but over time, increased the number of lesions make the capacity of the system outdated. Oxidative lesions also accumulate in people who have Huntington's disease, but the absence of extra segments on the Huntington gene does not lead to manifestations. Although scientists have hypothesized that oxidative lesions play an important role in Huntington's disease for a long time, the appropriate place of injury is still unknown.

"No one has yet linked these indicators with each other." McMurray says. To show that further segments grow in time, the researchers inserted the human genome in mice, which contained a Huntington gene with an inserted segment and big enough for the disease to be manifest in humans. Over several months - when mice were much older - researchers analyzed gene and found that the segment is high.

Because Huntington's disease affects the mind, body, and emotions, symptoms often mimic other conditions. The general symptoms of Huntington’s disease in early stages can include poor memory; difficulty making decisions; mood changes such as increased depression, anger or irritability; a growing lack of coordination, twitching or other uncontrolled movements; difficulty walking, speaking, and/or swallowing. The order in which symptoms develop will vary from person to person. This disease generally develops in adult people.

A brief history of the disease - Lupus is a disease known for over 2000 years. Hippocrates, who lived between 460 and 370, described the first consequences of this disease. The name lupus is derived from the Latin word which means wolf and was used to refer to ulcers of the face. In 1851, Cazenave made known a disease called lupus erythematosus. Later, on in the late 1800, Kaposi described the eruptions on the face of Sir William Osler, a Canadian physician, who has enlarged the concept of lupus, calling it a systemic disease that can affect many parts of the body.



What is lupus? - Lupus is a chronic disease that manifests a variety of symptoms and is caused by inflammation in one or more parts of the body. Lupus is not infectious, so it is not contagious (cannot be taken from one person to another, such as flu or measles ). It is not a form of cancer. And there is absolutely no connection between lupus and AIDS.

Lupus is part of the family of diseases that are included in rheumatoid arthritis, multiple sclerosis, juvenile diabetes and scleroderma (a disease manifested by thickening of skin and subcutaneous cellular tissue). The phases of Lupus disease consist of • a flare, with severe acute symptoms that require medical attention • a chronic phase, the symptoms may continue, but are less severe • remission, when symptoms may disappear completely for longer periods.

Types of Lupus - The most common form of lupus is systemic lupus erythematosus. It is a complex and complicated disease that can affect any tissue or organ of the body, including skin, muscles, joints, blood and blood vessels, lungs, heart, kidneys and brain. Lupus erythematosus, discoid and subacute cutaneous lupus erythematosus are diseases in which skin rash and sensitivity to the sun are major problems, because internal organs are not affected and therefore it cannot be the case of an endanger life. However, both types of lupus may occur sometimes along with a systemic form of lupus.

Symptoms of Lupus disease - There are general symptoms of Lupus disease, which we highlight in the following, but some people may show only some of the possible symptoms of this disease. Because it can affect any tissue in the body, lupus is often difficult to identify and diagnose. Therefore it is called the disease with 1000 faces. Before you install specific lupus symptoms may occur and flu symptoms, accompanied by severe fatigue, an increase or unexplained sudden weight loss, headaches, hair loss, high blood pressure or changes in color of fingers.

Possible symptoms are these: • joint pain, sometimes accompanied by swelling, redness and warmth • a red rash on the cheekbones and nose • Extreme tiredness • unusual reaction to sunlight • an eruption with crusting • hurt small, usually painless that occur in the nose or mouth • chest pain, which intensified when the patient lies stretched or inspire • leg swelling • weight gain • seizures.

Lupus is a disease that can be healed? - Until now there has not been found a treatment that can lead to a complete cure of the disease. However, there are many scientists who work on the study of this disease, so patients who suffer from lupus are fully justified to hope that in the near future it will be found a special treatment for this disease.

What is the element spreading Lyme disease? Ticks! Ticks live in grass and bushes and they attach to an animal passing near them, called the host. Ticks are small and may be hard to see with the naked eye. Young ticks, or nymphs, are the size of poppy seeds.



Early symptoms of Lyme disease (Borreliosis) - Some of the early symptoms of Lyme disease include the affection of the skin, joints, nervous system and other systems or organs. Symptoms and their severity can vary from one person to another.

Symptoms of Lyme disease are often described in three separate stages of the disease, although not all patients pass through all stages: The first sign of infection is usually a circular rash, called erythema migration, which occurs in 1-2 weeks after infection, but can occur 30 days after tick bite.

This rash often has a characteristic appearance of a bull’s eye, with a central red dot surrounded an area of clean skin, in turn surrounded by a red zone that extends. It can occur as a solid red ring extending. The area may be warm to the touch and usually not painful, or itchy. The target-shaped rash may be more difficult to observe in people who have darker skin, which may look like a sore. The rash usually goes away in about one month. Although this rash is considered typical of Lyme disease, there are many patients who do not have it.

Together with the hives, the infected person may have flu-like symptoms, like swollen lymph nodes, fatigue, headache and muscle aches. If untreated, initial symptoms may disappear by themselves. But in some people, infection can spread to other parts of the body. At this stage of Lyme disease, symptoms usually occur within weeks after the tick’s sting. The patient may feel very tired and very ill, or may have hives in several areas, depending on the location of the sting.

Lyme disease can affect the heart, which can lead to irregular heartbeat or chest pain. It can spread to the nervous system, causing facial paralysis or tingling and numbness of the arms and legs. It can start to cause headache and stiff neck, which can be considered symptoms of meningitis. For heavier people the disease main cause swelling and pain in joints.

Complications of Lyme disease - The last stage of Lyme disease can occur if the disease was not detected early and treated appropriately. Symptoms of Lyme disease in the last stage can occur weeks or years after the sting that caused the infection and include arthritis, especially in knees and later deterioration of cognitive functions in adults.

So if you find yourself walking in the woods, you should remember that bears and cougars are not the only threats you are facing. There may be many other risks involved in your regular hike, and one of these risks is a bite from a tick, and the subsequent Lyme disease infection. Even though not all tick bites cause Lyme disease infections, those that do need to be checked carefully. And I know, Lyme disease is not such a bad disease, I mean it is not like, say, cancer or necrotizing fasciitis, but it can cause a bit of discomfort and, I think you would agree, it is better to be safe than sorry. Correct? So start paying attention to what happens with your body and start looking more carefully at the insect bites you are dealing with.

The Chrone disease is a chronic affection, which has remissions that could last for a life time. The severity of this affection varies from one patient to another. Some patients have quite light symptoms, while other patients have grave symptoms and complications. In rare cases, the Chrone’s disease symptoms can evolve and cause decease.



The Chrone disease diagnosis is realized taking into consideration the anamnesis and the general examination at the hospital. This diagnosis is later confirmed by the intestinal biopsy.

The Chrone disease can sometimes be difficult to diagnose. The first signs of the disease can be unspecific and can cause pain in the joints, followed by extreme fatigue. In some cases, the diagnosis is confirmed years later, after the disease already installed, because The Chrone’s disease symptoms appear progressively and in the early stages are not very serious. In time, there will appear lesions of the intestine, resulted from the chronic inflammation of the small intestine and these lesions can lead to ulcer.

The colon and anus can be examined by having a colonoscopy. This method consists of introducing a long and flexible device in the anus, which is surrounded by optic fibers and which is connected to a monitor capable of illustrating images from inside the small intestine.

Colonoscopy is a very efficient method because it can examine the entire colon. This method permits the doctors to do a biopsy which is necessary in order to confirm the diagnosis for Chrone’s disease. The corresponding exams include CT and RMN.

A lab exam of the stool is also necessary in order to identify the pathologic products at the level of the intestine, like blood, blood cells, infections, pus, bacteria or some parasites. The syndrome of the irritable colon is a functional affection and has less serious symptoms than the Chrone disease. Some of the common Chrone’s disease symptoms are abdominal pain, diarrhea and weight loss, poor appetite, fever, night sweats, rectal pain and rectal bleeding.

The different sub- types of Chrone’s disease and their symptoms are: Chrone’s colitis, which is an inflammation confined to the colon. Some of the symptoms are abdominal pain and bloody diarrhea. Chrone’s enteritis is an inflammation confined to the small intestine Obstruction of the small intestine also can take place. Chrone’s terminal ileitis is an inflammation that affects only the end of the small intestine- the part of the small intestine which is closest to the colon.

Chrone’s entero-colitis and ileo-colitis are terms which describe an inflammation that involve both the small intestine and the colon. Some of the symptoms are bloody diarrhea or abdominal pain. Chrone’s terminal ileitis and ileo-colitis are the most common types of Crohne's disease. Up to one third of patients with Chrone’s disease may have one or more of the following conditions: swelling of the tissue of the anal sphincter, development of ulcers and fissures, development of anal fistulae or development of peri-rectal abscesses.

There are many people who don’t know what are some symptoms of disease liver disease and they might start believing that they are suffering from an affliction of the liver, when they are really not. This is why, you should go to your doctor and see what they have to say about these things you are feeling, and you could also ask this specialist “what are some symptoms of liver disease?” The doctor will tell you what I am about to tell you right now.



The first symptom is jaundice - This is the main red flag of disease in the liver is Jaundice. If the jaundice is maintained, this is a sign that there might be something up with your gall bladder or liver. Jaundice means that your skin becomes of a dimmed yellow coloring, or it becomes orange. This change in color may even be seen in the whites of your eyes. Your liver is meant to make bile, but when the blood from the veins is not correctly processed, then you start developing jaundice. If you see symptoms of jaundice and you also get the flu, then you should go to a doctor and see if you have an infection in the gall bladder or you start developing hepatitis.

Oriental medicine notes that there are two types of jaundice that may occur, namely the Yin Jaundice and the Yang Jaundice. Yang Jaundice is recognized through a feeling of thirst, constipation, irregular heartbeat, problems with urination, distension in the abdomen and also the tongue turning yellow are the main red flags pointing to the fact that the jaundice has engulfed the entire body, and the skin changes color to something similar to the color of a tangerine. Oriental doctors believe this kind of jaundice appears because of too much heat combined with moisture.

Yin Jaundice is diagnosed when the skin, everywhere, as well as the whites of the eyes, become a pale yellow. This condition is accompanied by high fever, low appetite, throwing up, tiredness, distension in the abdomen, diarrhea, cold limbs, swelling and others.

The second symptom concerns digestion and appetite - The most common red flag of disease in the liver is a decrease of the appetite which will later result in losing weight. This is a situation that can grow in severity because of bad assimilation of protein and fats contained in the body.

The lowered appetite could cause an evolution towards Anemia, also including hepatocytes revealed by the scanner. Faced with nausea and diarrhea, the human body may become weakened. Sometimes, there is also blood in the vomited substances if the patient also suffers from ulcer or gastritis.

A third symptom would be a light color of the fecal matter - If the bile pigments are blocked from secretion because of an obstacle or obstruction in the bile duct, then the fecal matter eliminated by patients gains a more pale color and becomes of a lighter coloring. In addition, IBS symptoms and bowel movements can be seen during the initial stages of a liver disease.

The brain is a very soft and spongy mass of tissue. It is protected by the bones of the skull and three thin membranes called meninges. The eatery fluid which is called cerebrospinal fluid pads the brain. This fluid flows through the spaces between the meninges and through spaces within the brain which are called ventricles.



The brain directs the things we choose to do (like walking, talking or eating) and the things our body does without thinking (like breathing or winking). The brain is also in charge of our senses (sight, hearing, touch, taste, and smell), memory, emotions and personality.

There are three major parts of the brain that control different activities. These parts are the cerebrum, the cerebellum and the brain stem. The symptoms of brain tumors depend on tumor size, type and also location. Symptoms can be caused when a tumor presses on a nerve or damages a certain area of the brain. Symptoms can also be caused when the brain swells or fluid builds up within the skull.

These are the most common brain tumor disease symptoms: headaches, nausea or vomiting, changes in speech, vision or hearing, problems balancing or walking, changes in mood, personality or ability to concentrate, problems with memory, muscle jerking or twitching, numbness or tingling in the arms or legs.

These disease symptoms are not sure signs of a brain tumor. Other conditions also could cause these problems, but anyone with these symptoms should see a doctor as soon as possible, because only a doctor can diagnose and treat the problem. Because treatment can damage healthy cells and tissues, unwanted side effects are very common. These side effects depend on several factors, like the location of the tumor or the type and the extent of treatment. Side effects may not be the same for every person, and they may actually change from one treatment session to the next one.

Some of the treatment options are surgery. Patients often have a headache or are uncomfortable for the first few days after the surgery, but medicine can usually control the pain. Some patients have nausea for several hours after radiation treatment. The health care team can suggest several ways to help patients to cope with this problem. Radiation therapy also may cause patients to become very tired as treatment goes on. Relaxation is important, but doctors usually advise patients to try to stay as active as they possibly can.

The side effects of chemotherapy depend mainly on the drugs that the doctors prescribe. The most common side effects include fever, chills, nausea, vomiting, and loss of appetite or weakness. Some side effects may be relieved with medicine. At any stage of disease, people with brain tumors receive supportive care to prevent or control problems and to improve the comfort and quality of life during treatments. Patients may receive treatment to control pain and other symptoms for brain tumors.