The Krone disease is a chronic affection, with remissions that could last for a lifetime. The gravity of this affection differs from one patient to another. Some patients have relatively light symptoms, while other patients have serious symptoms and complications. In rare cases, the Krone’s disease symptoms can evolve and cause death.



The Krone disease diagnosis is realized taking into account the anamnesis and the general exam at the hospital. This diagnosis is later confirmed by the intestinal biopsy.

The Krone disease can sometimes be hard to diagnose. The first signs of the disease can be unspecific and can feel like pain in the joints, followed by extreme fatigue. In some cases, the diagnosis is confirmed years after the disease installed, because The Krone’s disease symptoms appear gradually and at the beginning are not very serious. In time, there will appear lesions of the intestine, resulted from the chronic inflammation of the intestine and these lesions lead to ulcer.

The colon and anus can be examined by performing a colonoscopy. This method consists of introducing a long and flexible device in the anus, which has optic fibers and which is connected to a monitor capable of illustrating images from inside the intestine.

Colonoscopy is very efficient because it can examine the entire colon. This method allows the doctors to do a biopsy which is necessary in order to confirm the diagnosis for Krone’s disease. The complementary exams include CT and RMN. A lab exam of the stool is also useful in order to identify the pathologic products at the level of the intestine, like blood, blood cells, infections, pus, bacteria or parasites.

The syndrome of the irritable colon is a functional affection and has less serious symptoms than the Krone disease. Some of the common Krone’s disease symptoms are abdominal pain, diarrhea and weight loss. Other common symptoms include poor appetite, fever, night sweats, rectal pain and rectal bleeding.

The different subtypes of Krone’s disease and their symptoms are: Krone’s colitis, which is an inflammation confined to the colon. Some of the symptoms are abdominal pain and bloody diarrhea. Krone’s enteritis is an inflammation confined to the small intestine Obstruction of the small intestine also can occur.

Krone’s terminal ileitis is an inflammation that affects only the end of the small intestine- the part of the small intestine closest to the colon. Krone’s entero-colitis and ileo-colitis are terms which describe an inflammation that involve both the small intestine and the colon. The symptoms are bloody diarrhea and abdominal pain. Krone’s terminal ileitis and ileo-colitis are the most common types of Crohn's disease. Up to one third of patients with Krone’s disease may have one or several of the following conditions: swelling of the tissue of the anal sphincter, development of ulcers and fissures, development of anal fistulae and development of peri-rectal abscesses.