Evolution Of Celiac Disease
Published on Jun 01 2010, in the categories: celiac disease
-Evolution of Celiac disease: Celiac disease is a chronic illness caused by consumption of gluten. Vilia intestinal are some small, elongated formations in the intestinal lumen which creates a surface of absorption of vitamins, sugars and other food nutrients. Regarding the people with Celiac disease, vilia intestinal become flattened and inflamed, which decreases intestinal absorption surface, with the advent of malabsorbtion secondary. Malabsorption, secondary to celiac disease, can cause iron deficiency with iron deficiency anemia, vitamin D deficiency rickets appearance (the child), osteopenia and osteoporosis (adult). A characteristic of celiac disease is deepening, that regression of symptoms.
Risk factors: Celiac disease is an immune disorder that occurs among genetically susceptible individuals, characterized by intestinal damage arising as a result of immune reactions to gluten ingestion. Disease risk is increased in families with a family history of significant collateral. 10% of people who have a first degree relative (mother, father, brother, sister, son, daughter) with Celiac disease develop the disease at a time. In genetically susceptible persons, Celiac disease can be triggered by different environmental factors, including viral and bacterial infections.
People often associate with Celiac disease and other diseases, such as:
- Herpetiforma dermatitis (most common in adults but can occur in children);
- Osteoporosis ;
- Type I diabetes (insulin-dependent diabetes);
- Autoimmune thyroiditis;
- Down syndrome;
- Sjogren's syndrome;
- Selective antibody deficiency (immunoglobulin A deficiency);
- Iron deficiency anemia (iron deficiency) or macrocytic anemia (folate deficiency).
-Consult specialist:

The following evolution of celiac disease in children require a pediatric advice:
- Rapid weight loss;
- Diarrhea lasting more than 1-2 weeks;
- Stagnation stature weighted;
- Fatigue or indisposition unjustified, especially if they last more than a week and not related to another known cause (e.g. cold, flu). People diagnosed with celiac disease (adults or children) need a medical occur whenever:
- Recurrence of symptoms (signs of the disease recur after an asymptomatic period) ;
- Marked fatigue or intense pain in stomach, appellant appeared with the symptoms;
- Diarrhea and weight loss, occurred in children with gluten-free diet;
- Persist evolution of celiac disease in some children who do not know exactly the diet (often parents do not know if children were out of food intake and other permits).

Investigations: Diagnosis of Celiac disease is often confused with other conditions such as food intolerance or irritable bowel syndrome due to similar symptoms. Celiac disease diagnosis is often one of exclusion of other diseases with similar symptoms but does not respond to treatment. Medical history, clinical examination and laboratory tests underlying diagnosis of Celiac disease. Diagnosis is confirmed by performing a biopsy of the small intestine, surgery performed during digestive endoscopy (video exploring the tube).
Blood immunological tests: Celiac disease triggers an immune system response to the emergence in excess of certain antibodies. In case of the suspicion of celiac disease are needed following the determination of antibodies:
- The TTG Ig: immunoglobulin (Ig A) and tissue antibodies of transglutamin (TAT);
- The EMA Ig: immunoglobulin A (Ig A) and EMA antibodies;
- The AGM Ig: immunoglobulin A (Ig A) and antigliadina antibodies (AGA). If immunological tests are positive, intestinal biopsy is performed to confirm the diagnosis.
Risk factors: Celiac disease is an immune disorder that occurs among genetically susceptible individuals, characterized by intestinal damage arising as a result of immune reactions to gluten ingestion. Disease risk is increased in families with a family history of significant collateral. 10% of people who have a first degree relative (mother, father, brother, sister, son, daughter) with Celiac disease develop the disease at a time. In genetically susceptible persons, Celiac disease can be triggered by different environmental factors, including viral and bacterial infections.
People often associate with Celiac disease and other diseases, such as:
- Herpetiforma dermatitis (most common in adults but can occur in children);
- Osteoporosis ;
- Type I diabetes (insulin-dependent diabetes);
- Autoimmune thyroiditis;
- Down syndrome;
- Sjogren's syndrome;
- Selective antibody deficiency (immunoglobulin A deficiency);
- Iron deficiency anemia (iron deficiency) or macrocytic anemia (folate deficiency).
-Consult specialist:

The following evolution of celiac disease in children require a pediatric advice:
- Rapid weight loss;
- Diarrhea lasting more than 1-2 weeks;
- Stagnation stature weighted;
- Fatigue or indisposition unjustified, especially if they last more than a week and not related to another known cause (e.g. cold, flu). People diagnosed with celiac disease (adults or children) need a medical occur whenever:
- Recurrence of symptoms (signs of the disease recur after an asymptomatic period) ;
- Marked fatigue or intense pain in stomach, appellant appeared with the symptoms;
- Diarrhea and weight loss, occurred in children with gluten-free diet;
- Persist evolution of celiac disease in some children who do not know exactly the diet (often parents do not know if children were out of food intake and other permits).

Investigations: Diagnosis of Celiac disease is often confused with other conditions such as food intolerance or irritable bowel syndrome due to similar symptoms. Celiac disease diagnosis is often one of exclusion of other diseases with similar symptoms but does not respond to treatment. Medical history, clinical examination and laboratory tests underlying diagnosis of Celiac disease. Diagnosis is confirmed by performing a biopsy of the small intestine, surgery performed during digestive endoscopy (video exploring the tube).
Blood immunological tests: Celiac disease triggers an immune system response to the emergence in excess of certain antibodies. In case of the suspicion of celiac disease are needed following the determination of antibodies:
- The TTG Ig: immunoglobulin (Ig A) and tissue antibodies of transglutamin (TAT);
- The EMA Ig: immunoglobulin A (Ig A) and EMA antibodies;
- The AGM Ig: immunoglobulin A (Ig A) and antigliadina antibodies (AGA). If immunological tests are positive, intestinal biopsy is performed to confirm the diagnosis.
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