Pathophysiological mechanism
Researchers have found some changes taking place in the brain of people with Alzheimer's. These include:

Low levels of acetylcholine in certain brain areas-Caterpillar boards, which consist of agglomerations of abnormal nerve cells surrounding amyloid deposits (abnormal protein) and components neurofibrilare, piles of material that interrupt normal nerve cell structure. Senile plaques and these nodes neurofibrilare are usually seen at autopsy. These changes in the brain can cause memory loss and other symptoms of Alzheimer's disease. It is not known why these changes occur in some people and at others do not appear. Alzheimer's disease progresses over time, but the speed of progress depends from one person to another. Some events may have minimal until the late stages of disease.



Other people lose the ability to perform daily activities early during the disease.
Symptoms get progressively worse. At first, the disease is manifested by minor memory loss and progresses to severe functional and mental problems and even death. Symptoms are usually divided as those appearing in the initial phase, middle or late. It is difficult to say how long each phase is. An average person lives 8-10 years after symptoms appear. In this article, I'll offer you the most important things you should know about Alzheimer's disease stages signs symptoms.

The initial phase

Usually the initial stage of Alzheimer's Handful:

- Gets confused on the direction and easily lost

- Lose the ability to initiate certain activities

- Avoid new and unfamiliar situations

- Have delayed reactions and slow storage capacity

- Speaks less often than in the past

- Has difficulty handling money and paying bills

- Has troubles of law and wrong decisions

- May have mood disorders and become depressed, irritable or restless.

These symptoms are often obvious when a person is in a place or a new situation, unfamiliar.

Intermediate phase of Alzheimer's disease stages signs symptoms

Intermediate stage Alzheimer's patient manifests:

- Problems recognizing family and friends

- Anxiety, especially in the afternoon and evening

- Problems reading, writing and interpreting numbers

- Thinking and logic problems

- Unable to find specific words or up stories to replace what he forgot

- Difficulties in single dress

- Mood disorders, gets upset easily and become hostile to cooperation

- False beliefs (disappointment), suspicion (paranoid) and agitation

- Require constant care

- Lose temporal orientation

Late phase

Late phase, advanced Alzheimer's disease, patients:
- Not even remember how to wash, dress, go to the bathroom or eat without help. These people may be forced to stay in bed or wheelchair because forget to go

- Lose the ability to chew or swallow

- Have difficulty maintaining balance or walking and often fall because of this

- Become extremely confused and have insomnia tonight

- Cannot communicate with words

- Lose control of bladder or bowel control (incontinence)

During late Alzheimer's disease, patients become more susceptible to other illnesses. In some cases, seizures can occur. Death occurs as a complication of pneumonia due to immobilization in bed.